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1. How does Kaopectate work? |
A - Bismuth subsalicylate,
the new active ingredient in Kaopectate, controls diarrhea
within 24 hours. Although the exact mechanism is unknown,
it is believed to work by several mechanisms in the gut:
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It reduces symptoms of diarrhea by
slowing intestinal secretions, which decreases fluid
loss in diarrhea patients.
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It may inhibit the synthesis
of prostaglandins which are responsible
for intestinal contractions and inflammation.
-
It
may have an antimicrobial effect against numerous
diarrheal pathogens. It binds with the toxins produced
by the
bacteria.
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2. How is the new formula an improvement
over the old? |
A - The new formula contains
the active ingredient bismuth subsalicylate, which has been
proven in clinical studies to be more effective than the
active ingredient in the old formula.
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3. What flavors/sizes does Kaopectate
come in? |
A - The new Kaopectate formula
is currently available in liquid form and will be available
caplet form later in 2003. The 2 adult liquids come in regular
(vanilla) and peppermint flavors and are available in 8-
and 12oz bottles. Kaopectate is also available in a 6oz Children’s
liquid formula in a great tasting cherry flavor, and an 8oz
Extra Strength liquid formula in peppermint. Kaopectate caplets
are available in the old formula and will be available in
the new formula later in 2003. Caplets come in 12- and 20-
count boxes.
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4. When should I take Extra Strength
Kaopectate over the regular strength? |
A - The Extra Strength formula
contains twice the active ingredient per tablespoonful than
the regular strength formula allowing you to relieve your
diarrhea with fewer doses. You should take Extra Strength
if your diarrhea is more severe and/or you want to limit
the number of doses you need to take before you get relief.
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5. Can I give Kaopectate to my children? |
A - Kaopectate liquid and caplets
are approved for use by children down to age 3, however we
recommend children between the ages of 3 and 8 use Children’s
Kaopectate liquid. For children under the age of 3, consult
with your doctor.
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6. The new formula sometimes darkens
the tongue/stool. Why does this happen and how long does
it last? |
A - Kaopectate may cause a
harmless darkening of the tongue or stool that is caused
when the active ingredient (bismuth subsalicylate) combines
with the healthy bacteria in your saliva and gastrointestinal
(GI) tract and forms a black-colored substance called bismuth
sulfide. It is not an alarming sign and should go away within
several days after you stop using the medication. You do
not need to stop using the product as a result of this harmless
and temporary side effect. If the discoloration of the stool
does not subside after discontinuing use, however, consult
your physician, as this may be a sign of a more serious condition.
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7. What is salicylate? Is it a form
of aspirin? |
A - Salicylate is a substance
that is present in aspirin. It possesses analgesic (pain
killing) and anti-inflammatory properties. Bismuth subsalicylate,
the active ingredient in Kaopectate liquids, is related to
aspirin.
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8. How are salicylates associated with
allergies and Reye’s syndrome? |
A - Allergic reactions to salicylates
have been noted in patients with known hypersensitivity to
aspirin and related compounds.|
While the exact cause of Reye’s syndrome is not completely
understood, the risk of Reye’s syndrome can increase
when you take aspirin or other salicylates while suffering
or recovering from the chicken pox, flu or flu symptoms.
Reye’s syndrome has been associated with salicylate administration
during viral illness. Children and teenagers who have or are
recovering from chicken pox, flu symptoms or flu should not
use this product. If nausea, vomiting or fever occur, consult
a doctor because this could be an early sign of Reye’s
syndrome, a rare but serious illness.
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9. If I'm allergic to aspirin, can
I take this product? |
A - No. You should not use
this product if you are allergic to aspirin or other salicylates.
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10. Can I still buy the old Kaopectate
formula? |
A - Yes. The old formula is
still available in caplet form and will be until later in
2003. At that time, the caplets will also be reformulated
and the old formula will no longer be available.
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11. I can’t find the caplets
in the new formula. Are they available? |
A - Kaopectate caplets are
also being reformulated, but the new formula won’t
be available until later in 2003. The old formula is still
available in the stores where you shop.
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12. Can I refrigerate Kaopectate? |
A - Although storage under
typical refrigeration conditions (36º – 40º F) is not
likely to have an impact on the performance of the product,
we recommend you store the product at 66º – 77º F.
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13. When can I take Kaopectate? Do
I need to take it with food? |
A - Follow the directions on
the label. You do not need to take it with food.
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14. Can pregnant or nursing women take
Kaopectate? |
A - If pregnant or breast-feeding,
ask a health professional before use.
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